Cerebrospinal beta-amyloid peptides(1-40) and (1-42) in severe preeclampsia and HELLP syndrome – a pilot study
نویسندگان
چکیده
منابع مشابه
Plasma beta carotene in Alzheimer's disease. Association with cerebrospinal fluid beta-amyloid 1-40, (Abeta40), beta-amyloid 1-42 (Abeta42) and total Tau.
We studied the plasma beta carotene concentrations in 40 Alzheimer's disease patients and the association with cerebrospinal fluid beta-amyloid 1-40, (Abeta40), cerebrospinal fluid beta-amyloid 1-42 (Abeta42) and cerebrospinal fluid total Tau. We found that patients with plasma beta carotene levels below the 25th percentile had 55% reduced ratios of Abeta40/Tau and 51% reduced ratios of Abeta 4...
متن کاملEarly preeclampsia and HELLP syndrome in a 20 week pregnant patient
The first time Weinstein in 1982 described patients with the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP) in pregnant preeclamptic and eclamptic patients. This syndrome is a severe form of preeclampsia or eclampsia. Usually HELLP syndrome occurs at the third trimester and only 15% occur before the 27th week of pregnancy and rarely before the 20th week of pregna...
متن کاملToxicity of amyloid beta 1-40 and 1-42 on SH-SY5Y cell line
MicroRNAs (miRNAs) are short, 22–25 nucleotide long transcripts that may suppress entire signaling pathways by interacting with the 3’-untranslated region (3’-UTR) of coding mRNA targets, interrupting translation and inducing degradation of these targets. The long 3’-UTRs of brain transcripts compared to other tissues predict important roles for brain miRNAs. Supporting this notion, we found th...
متن کاملCerebrospinal fluid and -amyloid(1-42) in dementia disorders
The reliability of cerebrospinal fluid (CSF)and CSF-amyloid assays for diagnosis of Alzheimer’s disease and other dementing disorders such as frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and Creutzfeldt–Jakob disease (CJD) is reviewed. CSF assessment of the two proteins is useful in early diagnosis of AD and to differentiate it from FTD and DLB. Extremely high CSFlevels can di...
متن کاملHELLP syndrome. Women with partial HELLP syndrome (PHS) should be studied and managed separately from women with HELLP syndrome or severe preeclampsia. The incidence of HELLP syndrome
Hemolysis, elevated liver enzymes and low platelet count are alterations in laboratory tests that are found in pregnant or post-delivery women who have preeclampsia. The term HELLP syndrome was coined for this set of alterations by Weinstein in 1982. Since then many reports have been presented, but the quantification of laboratory tests has differed among them. Since Sibai proposed strict crite...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2020
ISSN: 2045-2322
DOI: 10.1038/s41598-020-62805-2